| Name | EDOS-2 - Early Detection of Osteoporosis in Space |
| Operational Nomenclature | EDOS-2 |
| URL | https://hreda.esac.esa.int/hreda/#/pages/investigation;investigationAcronym=EDOS_2_ISS |
| DOI | https://doi.org/10.57780/esa-nsf14tw |
| Platform | ISS |
| HRE-E3P Category | Human Research |
| Mission | Inc43, Inc44, Inc45, Inc46, Inc47, Inc48, Inc49, Inc50, Inc51, Inc52, Inc59, Inc60, Inc61, Inc62, Inc63, Inc64, Inc66, Inc67, Inc68, Inc69 |
| Keywords | ESA Human and Robotic Exploration data, HREDA dataset, Human and Robotic Exploration Data Archive, ESA exploration mission data, human spaceflight experiment data, robotic exploration telemetry dataset, International Space Station experiment data, ISS Columbus module data, microgravity research dataset, life sciences space experiment data, space physiology measurements dataset, radiation exposure measurements spaceflight, life support systems performance data, closed-loop environmental control data, ECLSS telemetry dataset, astronaut biomedical monitoring data, space habitat systems engineering data, robotic surface operations dataset, planetary exploration robotics data, lunar exploration technology demonstration data, Mars analog experiment dataset, in-situ resource utilization ISRU experiment data, space systems engineering telemetry, mission operations engineering data, payload performance dataset, calibrated experiment data products, time-series telemetry data, spaceflight sensor measurements, ESA exploration science archive data, long-duration spaceflight research dataset |
| Team Coordinator Name | Laurence Vico |
| Version | 1.0 |
| Team Members | EDOS_2_ISS |
| Publication | Jörn Rittweger, HM Frost, H Schiessl, H Ohshima, B Alkner, Per A. Tesch, Dieter Felsenberg, 2005, Muscle atrophy and bone loss after 90 days of bed rest and the effects of Flywheel resistive exercise and Pamidronate: Results from the LTBR study, Bone, 36, 1019-1029 Jörn Rittweger, Boštjan Šimunič, G Bilancio, N Gaspare De Santo, M Cirillo, Gianni Biolo, Rado Pišot, O Eiken, Igor B. Mekjavić, Marco Narici, 2009, Bone loss in the lower leg during 35 days of bed rest is predominantly from the cortical compartment, Bone, 44, 612-618 Gabriele Armbrecht, DL Belavý, Ulf Gast, M Bongrazio, F Touby, G Beller, HJ Roth, FH Perschel, Jörn Rittweger, Dieter Felsenberg, 2010, Resistive vibration exercise attenuates bone and muscle atrophy in 56-days of bed-rest: biochemical markers of bone metabolism, Osteoporosis International, 21, 4, 597-607, DOI 10.1007/s00198-009-0985-z Jörn Rittweger, G Beller, Gabriele Armbrecht, E Mulder, B Buehring, Ulf Gast, F Dimeo, H Schubert, A de Haan, DF Stegeman, H Schiessl, Dieter Felsenberg, 2010, Prevention of bone loss during 56 days of strict bed rest by side-alternating resistive vibration exercise, Bone, , 137-147, PMID: 19732856 Laurence Vico, B van Rietbergen, N Vilayphiou, Marie-Thérèse Linossier, Hervé Locrelle, Myriam Normand, M Zouch, M Gerbaix, N. Bonnet, V Novikov, T Thomas, G Vassilieva, 2017, Cortical and trabecular bone microstructure did not recover at weightbearing skeletal sites and progressively deteriorated at non-weight-bearing sites during the year following International Space Station missions, Journal of Bone and Mineral Research, 32(10), DOI 10.1002/jbmr.3188, 2010-2021 Jörn Rittweger, K Winwood, O Seynnes, MD De Boer, D Wilks, R Lea, M Rennie, Marco Narici, 2006, Bone loss from the human distal tibia epiphysis during 24 days of unilateral limb suspension, The Journal of Physiology, 577, 331-337 M Baecker, A Tomic, C Mika, A Gotzmann, P Platen, Ruppert Gerzer, Martina Heer, 2003, Bone resorption is induced on the second day of bed rest: results of a controlled crossover trial, Journal of Applied Physiology, 95, 977 |
| Temporal Coverage | 2015-03-12T00:00:00Z/2023-09-20T00:00:00Z |
| Mission Description | The HRE Data Archive (HREDA) collects information and data of investigations funded or co-funded by ESA’s Directorate for Human and Robotic Exploration (HRE) and performed on microgravity and ground-based facilities since 1972. |
| Creator Contact | https://hreda.esac.esa.int/hreda/#/pages/help/contact |
| Date Published | 2025-11-07T11:36:42Z |
| Last Update | 2026-07-09 |
| Publisher And Registrant | European Space Agency |
| Credit Guidelines | European Space Agency, Laurence Vico, 2025, 'EDOS-2', 1.0, European Space Agency, https://doi.org/10.57780/esa-nsf14tw |
| Rights | Data hosted in the ESA Space Science Archives are distributed under the CC BY-NC 3.0 IGO license. |