| Name | Protein Kinase C Isozyme Translocations Kinetics in Microgravity and Variable Gravity Environments |
| Operational Nomenclature | Protein Kinase C Isozyme Translocations Kinetics |
| URL | https://hreda.esac.esa.int/hreda/#/pages/investigation;investigationAcronym=ProteinKinase_C_Isozyme_SHUT |
| DOI | https://doi.org/10.57780/esa-3kl7k5j |
| Platform | Space Shuttle |
| HRE-E3P Category | Biology |
| Mission | STS-81 (Shuttle-to-MIR mission 05: S/MM 05) |
| Keywords | ESA Human and Robotic Exploration data, HREDA dataset, Human and Robotic Exploration Data Archive, ESA exploration mission data, human spaceflight experiment data, robotic exploration telemetry dataset, International Space Station experiment data, ISS Columbus module data, microgravity research dataset, life sciences space experiment data, space physiology measurements dataset, radiation exposure measurements spaceflight, life support systems performance data, closed-loop environmental control data, ECLSS telemetry dataset, astronaut biomedical monitoring data, space habitat systems engineering data, robotic surface operations dataset, planetary exploration robotics data, lunar exploration technology demonstration data, Mars analog experiment dataset, in-situ resource utilization ISRU experiment data, space systems engineering telemetry, mission operations engineering data, payload performance dataset, calibrated experiment data products, time-series telemetry data, spaceflight sensor measurements, ESA exploration science archive data, long-duration spaceflight research dataset |
| Team Coordinator Name | Jason P. Hatton |
| Version | 1.0 |
| Team Members | ProteinKinase_C_Isozyme_SHUT |
| Publication | Jason P. Hatton, F Gaubert, ML Lewis, Y Darsel, P Ohlmann, Jean Pierre Cazenave, Didier A. Schmitt, 1999, The kinetics of translocation and cellular quantity of protein kinase C in human leukocytes are modified during spaceflight, The FASEB Journal, Vol. 13, 23-33 Jason P. Hatton, F Gaubert, Jean Pierre Cazenave, Didier A. Schmitt, 2002, Microgravity Modifies Protein Kinase C Isoform Translocation in the Human Monocytic Cell Line U937 and Human Peripheral Blood Cells, J. Cell. Biochem., Vol. 87, 39-50 Jason P. Hatton, A Lepage, P Howley, Jean Pierre Cazenave, Didier A. Schmitt, F Gaubert, Y Darsel, SB Roquefeuil, ML Lewis, 1999, The effect of microgravity on PKC mediated signal transduction in human leukocites: the S/MM-03 Phorbol, S/MM-05 Isozyme and S/MM-06 Cytokine experiments, Biorack on Spacehab, ESA SP-1222, 43-54, M Perry |
| Temporal Coverage | 1997-01-12T00:00:00Z/1997-01-22T00:00:00Z |
| Mission Description | The HRE Data Archive (HREDA) collects information and data of investigations funded or co-funded by ESA’s Directorate for Human and Robotic Exploration (HRE) and performed on microgravity and ground-based facilities since 1972. |
| Creator Contact | https://hreda.esac.esa.int/hreda/#/pages/help/contact |
| Date Published | 2025-11-08T13:34:27Z |
| Last Update | 2026-03-04 |
| Publisher And Registrant | European Space Agency |
| Credit Guidelines | European Space Agency, Jason P. Hatton, 2025, 'Protein Kinase C Isozyme Translocations Kinetics', 1.0, European Space Agency, https://doi.org/10.57780/esa-3kl7k5j |