| Name | Effect of Microgravity on Cellular Action: The Role of Cytokines |
| Operational Nomenclature | Cellular Action: The Role of Cytokines |
| URL | https://hreda.esac.esa.int/hreda/#/pages/investigation;investigationAcronym=CellularAction_Cytokines_SHUT |
| DOI | https://doi.org/10.57780/esa-ekr23lu |
| Platform | Space Shuttle |
| HRE-E3P Category | Biology |
| Mission | STS-65, IML-2 |
| Keywords | ESA Human and Robotic Exploration data, HREDA dataset, Human and Robotic Exploration Data Archive, ESA exploration mission data, human spaceflight experiment data, robotic exploration telemetry dataset, International Space Station experiment data, ISS Columbus module data, microgravity research dataset, life sciences space experiment data, space physiology measurements dataset, radiation exposure measurements spaceflight, life support systems performance data, closed-loop environmental control data, ECLSS telemetry dataset, astronaut biomedical monitoring data, space habitat systems engineering data, robotic surface operations dataset, planetary exploration robotics data, lunar exploration technology demonstration data, Mars analog experiment dataset, in-situ resource utilization ISRU experiment data, space systems engineering telemetry, mission operations engineering data, payload performance dataset, calibrated experiment data products, time-series telemetry data, spaceflight sensor measurements, ESA exploration science archive data, long-duration spaceflight research dataset |
| Team Coordinator Name | Didier A. Schmitt |
| Version | 1.0 |
| Publication | Didier A. Schmitt, Jason P. Hatton, 1997, Effect of microgravity on cellular activation in lymphocytes: protein kinase C signal transduction (Phorbol) and cytokine synthesis (Cytokine), Second International Microgravity Laboratory (IML-2) - Final Report, NASA CP 1405, 122-123, RS Snyder Didier A. Schmitt, 1992, Microlab: a set-up developed to perform experiments in extreme conditions like parabolic plane flight, Microgravity Sci. Technol., Vol. 5, No. 2, 109-111 Didier A. Schmitt, P Ohlmann, C Gachet, Jean Pierre Cazenave, 1993, Platelet shape change and protein phosphorylation induced by ADP and thrombin are not sensitive to short periods of microgravity, J. Cell Sci., Vol. 104, 805-810 Didier A. Schmitt, L Schaffar, 1993, Isolation and confinement as a model for spaceflight immune changes, J. Leukocyte Biol., Vol. 54, 209-213 PJ Parker, 1994, Protein kinase C: History and perspectives, Protein Kinase C, , 3-15, JF Kuo, Oxford University Press Didier A. Schmitt, Jason P. Hatton, C Emond, Didier Chaput, H Paris, T Levade, Jean Pierre Cazenave, L Schaffar, 1996, The distribution of protein kinase C in human leukocytes is altered in microgravity, The FASEB Journal, Vol. 10, 1627-1634 Didier A. Schmitt, 1991, Gravity effects on single cells: techniques, findings and theory, Adv. Space Biol. Med., Vol. 1, 183-248 |
| Temporal Coverage | 1994-07-08T00:00:00Z/1994-07-23T00:00:00Z |
| Mission Description | The HRE Data Archive (HREDA) collects information and data of investigations funded or co-funded by ESA’s Directorate for Human and Robotic Exploration (HRE) and performed on microgravity and ground-based facilities since 1972. |
| Creator Contact | https://hreda.esac.esa.int/hreda/#/pages/help/contact |
| Date Published | 2025-11-06T19:33:07Z |
| Last Update | 2026-03-04 |
| Publisher And Registrant | European Space Agency |
| Credit Guidelines | European Space Agency, Didier A. Schmitt, 2025, 'Cellular Action: The Role of Cytokines', 1.0, European Space Agency, https://doi.org/10.57780/esa-ekr23lu |