| Name | Lipoxygenase Activity in Microgravity |
| Operational Nomenclature | Lipoxygenase Activity |
| URL | https://hreda.esac.esa.int/hreda/#/pages/investigation;investigationAcronym=LipoxygenaseActivity_PARA |
| DOI | https://doi.org/10.57780/esa-msoffrj |
| Platform | Parabolic Airplanes |
| HRE-E3P Category | Biology |
| Mission | 28th ESA Parabolic Flight Campaign |
| Team Coordinator Name | M Maccarrone, GA Veldink |
| Version | 1.0 |
| Team Members | LipoxygenaseActivity_PARA |
| Publication | M Maccarrone, N Battista, MA Meloni, Monica Bari, G Galleri, P Pippia, Augusto Cogoli, A Finazzi-Agro, 2003, Creating conditions similar to those that occur during exposure of cells to microgravity induces apoptosis in human lymphocytes by 5-lipoxygenase-mediated mitochondrial uncoupling and cytochrome c release, Journal of Leukocyte Biology, 73, 4, 472-481 Battista, C Rapino, V Gasperi, A Finazzi-Agro, M Maccarrone, 2007, Effect of RNAlater on lipoxygenase activity and expression, and immune cell apoptosis: opening the gate to the, Journal of Gravitational Physiology, 14, 131-132 Battista, MA Meloni, Monica Bari, N Mastrangelo, G Galleri, C Rapino, E Dainese, A Finazzi-Agro, P Pippia, M Maccarrone, 2012, 5-Lipoxygenase-dependent apoptosis of human lymphocytes in the International Space Station: data from the ROALD experiment, The FASEB Journal, 26, 5, 1791-1798, DOI: 10.1096/fj.11-199406 M Maccarrone, N Battista, MA Meloni, Monica Bari, G Galleri, P Pippia, Augusto Cogoli, A Finazzi-Agro, 2003, Simulated microgravity induces apoptosis in human lymphocytes by a 5-lipoxygenase-mediated mechanism, Journal of Biological Research, LXXIX, 63-64 M Maccarrone, A Finazzi-Agro, 2001, Microgravity increases the affinity of lipoxygenases for free fatty acids, FEBS Letters, 489, 2, 283 M Maccarrone, N Battista, Monica Bari, A Finazzi-Agro, 2002, Lipoxygenase and apoptosis in microgravity, Journal of Gravitational Physiology, 9, 1, 241-244 M Maccarrone, A Finazzi-Agro, 2003, The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis, Cell Death and Differentiation, 10, 946-955, doi:10.1038/sj.cdd.4401284 M Maccarrone, Monica Bari, A Finazzi-Agro, 1999, Lipid peroxidation and polyamine metabolism in K562 cells subjected to altered gravity, Journal of Gravitational Physiology, 6, 1, P25-26 M Maccarrone, Monica Bari, T Lorenzon, A Finazzi-Agro, 2000, Altered gravity modulates prostaglandin H synthase in human K562 cells, Journal of Gravitational Physiology, 7, 2, P61-62 M Maccarrone, A Finazzi-Agro, 2001, Enzyme activity in microgravity: a problem of catalysis at the water-lipid interface?, FEBS Letters, 504, 1, 80 M Maccarrone, Monica Bari, N Battista, A Finazzi-Agro, 2001, The catalytic efficiency of soybean lipoxygenase-l is enhanced at low gravity, Biophysical Chemistry, 90, 97-101 |
| Temporal Coverage | 2000-05-24T00:00:00Z/2000-05-26T00:00:00Z |
| Mission Description | The HRE Data Archive (HREDA) collects information and data of investigations funded or co-funded by ESA’s Directorate for Human and Robotic Exploration (HRE) and performed on microgravity and ground-based facilities since 1972. |
| Creator Contact | https://hreda.esac.esa.int/hreda/#/pages/help/contact |
| Date Published | 2024-09-04T19:17:53Z |
| Last Update | 2024-11-21 |
| Publisher And Registrant | European Space Agency |
| Credit Guidelines | European Space Agency, 2024, 'Lipoxygenase Activity', 1.0, European Space Agency, https://doi.org/10.57780/esa-msoffrj |