| Name | Regulation of Cell Growth and Differentiation by Microgravity: Retinoic Acid-induced Cell Differentiation |
| Operational Nomenclature | Retinoic Acid-induced Cell Differentiation |
| URL | https://hreda.esac.esa.int/hreda/#/pages/investigation;investigationAcronym=RetinoicAcid_induced_CellDifferentiation_SHUT |
| DOI | https://doi.org/10.57780/esa-7bh8olo |
| Platform | Space Shuttle |
| HRE-E3P Category | Biology |
| Mission | STS-65, IML-2 |
| Team Coordinator Name | SW De Laat |
| Version | 1.0 |
| Publication | PJ Rijken, J Boonstra, AJ Verkleij, SW De Laat, 1994, Effects of gravity on the cellular response to epidermal growth factor, Adv. Space Biol. Med., Vol. 45, 159-188 J Boonstra, 1999, Growth factor-induced signal transduction in adherent mammalian cells is sensitive to gravity, FASEB J., Vol. 13, S35-S42 J Boonstra, PJ Rijken, RP De Groot, AJ Verkleij, PT Van der Saag, SW De Laat, 1997, Growth factor-induced signal transduction in mammalian cells is sensitive to gravity, Frontiers of Biological Science in Space, , 2-18, A Sato, Taiyo Printings Sales Co., Ltd., Toky SW De Laat, 1997, Replication of cell growth and differentiation by microgravity: retinoic acid-induced cell differentiation (Mouse), Second International Microgravity Laboratory (IML-2) - Final Report, NASA RP-1405, 130-131, RS Snyder J Boonstra, 1997, Growth factor-induced signal transduction in mammalian cells is sensitive to gravity, Life Sciences Experiments Performed on Sounding Rockets (1985-1994), ESA SP-1206, 53-57, Augusto Cogoli, U Friedrich, D Mesland, René Demets PJ Rijken, RP De Groot, W Kruijer, SW De Laat, AJ Verkleij, J Boonstra, 1992, Identification of specific gravity sensitive signal transduction pathways in human A431 carcinoma cells, Adv. Space Res., Vol. 12, 145-152 PJ Rijken, RP De Groot, W Briegleb, W Kruijer, AJ Verkleij, J Boonstra, SW De Laat, 1991, Epidermal growth factor-induced cell rounding is sensitive to simulated gravity, Aviat. Space Env. Med., Vol. 62, 32-36 RP De Groot, PJ Rijken, J den Hertog, J Boonstra, AJ Verkleij, SW De Laat, W Kruijer, 1991, Nuclear responses to protein kinase C signal transduction are sensitive to gravity changes, Experimental Cell Research, 197, 1, 87-90 RP De Groot, PJ Rijken, J den Hertog, J Boonstra, AJ Verkleij, SW De Laat, W Kruijer, 1990, Microgravity decreases c-fos induction and serum response element (SRE) activity, J. Cell Science, Vol. 97, 33-38 |
| Temporal Coverage | 1994-07-08T00:00:00Z/1994-07-23T00:00:00Z |
| Mission Description | The HRE Data Archive (HREDA) collects information and data of investigations funded or co-funded by ESA’s Directorate for Human and Robotic Exploration (HRE) and performed on microgravity and ground-based facilities since 1972. |
| Creator Contact | https://hreda.esac.esa.int/hreda/#/pages/help/contact |
| Date Published | 2024-07-22T16:18:14Z |
| Last Update | 2025-01-25 |
| Publisher And Registrant | European Space Agency |
| Credit Guidelines | European Space Agency, 2024, 'Retinoic Acid-induced Cell Differentiation', 1.0, European Space Agency, https://doi.org/10.57780/esa-7bh8olo |