| Name | Influence of Microgravity on Different Metabolic Potentials of Intestinal Microflora |
| Operational Nomenclature | Metabolic Potentials of Intestinal Microflora |
| URL | https://hreda.esac.esa.int/hreda/#/pages/investigation;investigationAcronym=MetabolicPotentials_IntestinalMicroflora_SHUT |
| DOI | https://doi.org/10.57780/esa-em30xbc |
| Platform | Space Shuttle |
| HRE-E3P Category | Biology |
| Mission | STS-40, SLS-1 |
| Keywords | ESA Human and Robotic Exploration data, HREDA dataset, Human and Robotic Exploration Data Archive, ESA exploration mission data, human spaceflight experiment data, robotic exploration telemetry dataset, International Space Station experiment data, ISS Columbus module data, microgravity research dataset, life sciences space experiment data, space physiology measurements dataset, radiation exposure measurements spaceflight, life support systems performance data, closed-loop environmental control data, ECLSS telemetry dataset, astronaut biomedical monitoring data, space habitat systems engineering data, robotic surface operations dataset, planetary exploration robotics data, lunar exploration technology demonstration data, Mars analog experiment dataset, in-situ resource utilization ISRU experiment data, space systems engineering telemetry, mission operations engineering data, payload performance dataset, calibrated experiment data products, time-series telemetry data, spaceflight sensor measurements, ESA exploration science archive data, long-duration spaceflight research dataset |
| Team Coordinator Name | O Szylit |
| Version | 1.0 |
| Team Members | MetabolicPotentials_IntestinalMicroflora_SHUT |
| Publication | DH Calloway, EL Murphy, 1969, Intestinal hydrogen and methane of men fed space diet, Life Sciences & Space Research, Vol. VII, 102-109 AH Merrill, 1993, Altered carbohydrate, lipid and xenobiotic metabolism by liver from rats flown on Cosmos 1887, FASEB J., Vol. 4, 95-100 Roland, 1993, Interactions between the intestinal flora and xenobiotic metabolising enzymes and their health consequences, World Rev. Nutr. Diet., Vol. 74, 123-148 HR Sawyer, 1990, Effects of space flight on the proliferation of jejunal mucosa cells, FASEB J., Vol. 4, 92-94 P Groza, 1988, Digestive reactions to simulated and real space flight, Physiologie, Vol. 25, 507-511 JC Meslin, 1993, Effects of galacto-oligosaccharide and bacterial status on mucine distribution in mucosa and on large intestine fermentation in rats, Brit. J. Nutr., Vol. 69, 903-912 O Szylit, L Nugon-Baudon, C Andrieux, S Rabot, JC Meslin, Michel Viso, 1994, Influence of microgravity on different metabolic potentials of intestinal microflora, Proc. Fifth European Symp. Life Sciences Research in Space, Arcachon, France, ESA SP-366, 433-438 René Tixador, G Richoilley, Gilbert Gasset, J Templier, JC Bes, Nicolle Moatti, L Lapchine, 1985, Study of minimal inhibitory concentration of antibiotics on bacteria cultivated in vitro in space (Cytos 2 experiment), Aviat. Space Environ. Med., Vol. 56, No. 8, 748-751 S Turroni, M Magnani, KC Pukar, P Lesnik, H Vidal, Martina Heer, 2020, Gut Microbiome and Space Travelers' Health: State of the Art and Possible Pro/Prebiotic Strategies for Long-Term Space Missions, Frontiers in Physiology, 11, 1135, DOI: 10.3389/fphys.2020.553929 WH Habig, 1974, Glutathione-S-transferases. The first enzymatic step in mercapturic acid formation, J. Biol. Chem., Vol. 249, 7130-7139 OH Lowry, 1951, Protein measurement with the Folin phenol reagent, J. Biol. Chem., Vol. 193, 265-275 O Szylit, C Andrieux, 1993, Physiological and pathophysiological effects of carbohydrate fermentation, World Rev. Nutr. Diet., Vol. 74, 88-122 |
| Temporal Coverage | 1991-06-05T00:00:00Z/1991-06-14T00:00:00Z |
| Mission Description | The HRE Data Archive (HREDA) collects information and data of investigations funded or co-funded by ESA’s Directorate for Human and Robotic Exploration (HRE) and performed on microgravity and ground-based facilities since 1972. |
| Creator Contact | https://hreda.esac.esa.int/hreda/#/pages/help/contact |
| Date Published | 2025-11-07T21:32:46Z |
| Last Update | 2026-03-04 |
| Publisher And Registrant | European Space Agency |
| Credit Guidelines | European Space Agency, O Szylit, 2025, 'Metabolic Potentials of Intestinal Microflora', 1.0, European Space Agency, https://doi.org/10.57780/esa-em30xbc |