
| Name | CHO2ICE II-Study - Consequence of Long-Term Confinement and Hypobaric Hypoxia on Immunity in the Antarctic Concordia Environment: FROM OBSERVATIONS TO MECHANISMS | 
| Operational Nomenclature | CHOI2CE II-Study | 
| URL | https://hreda.esac.esa.int/hreda/#/pages/investigation;investigationAcronym=CHO2ICE_II_Study_ANA | 
| DOI | https://doi.org/10.57780/esa-r3jf3ay | 
| Platform | Analogues | 
| HRE-E3P Category | Human Research | 
| Mission | CONCORDIA winter-over 2016, CONCORDIA winter-over 2017 | 
| Team Coordinator Name | Matthias Feuerecker, Alexander Chouker | 
| Version | 1.0 | 
| Team Members | CHO2ICE_II_Study_ANA | 
| Publication | A Stahn, HC Gunga, E Kohlberg, J Gallinat, DF Dinges, Simone Kühn, 2019, Brain Changes in Response to Long Antarctic Expeditions, The New England Journal of Medicine, 381, 23, , DOI: 10.1056/NEJMc1904905 Alexander Choukèr, AC Stahn, 2020, COVID-19 - The largest isolation study in history: the value of shared learnings from spaceflight analogs, npj Microgravity, 6, 1, 32, DOI: 10.1038/s41526-020-00122-8 Judith-Irina Buchheim, JN Billaud, Matthias Feuerecker, Claudia Strewe, C Dangoisse, Andreas Osterman, Satish Mehta, Brian E. Crucian, Gustav Schelling, Alexander Choukèr, 2020, Exploratory RNA-seq analysis in healthy subjects reveals vulnerability to viral infections during a 12-month period of isolation and confinement, Brain, Behavior, & Immunity - Health, 9, 100145, DOI: 10.1016/j.bbih.2020.100145 | 
| Temporal Coverage | 2015-10-01T00:00:00Z/2018-05-31T00:00:00Z | 
| Mission Description | The HRE Data Archive (HREDA) collects information and data of investigations funded or co-funded by ESA’s Directorate for Human and Robotic Exploration (HRE) and performed on microgravity and ground-based facilities since 1972. | 
| Creator Contact | https://hreda.esac.esa.int/hreda/#/pages/help/contact | 
| Date Published | 2024-02-25T12:18:07Z | 
| Last Update | 2025-09-10 | 
| Publisher And Registrant | European Space Agency | 
| Credit Guidelines | European Space Agency, 2024, 'CHOI2CE II-Study', 1.0, European Space Agency, https://doi.org/10.57780/esa-r3jf3ay |