| Name | OBLAST 1 - Osteoblastic cells in weightlessness: morphology and biochemical response |
| Operational Nomenclature | OBLAST 1 |
| URL | https://hreda.esac.esa.int/hreda/#/pages/investigation;investigationAcronym=OBLAST1_RETR |
| DOI | https://doi.org/10.57780/esa-cmpr6bm |
| Platform | Retrievable Facilities |
| HRE-E3P Category | Biology |
| Mission | Bion 10 (Cosmos 2229) |
| Team Coordinator Name | Christian Alexandre |
| Version | 1.0 |
| Team Members | OBLAST1_RETR |
| Publication | Millie Hughes-Fulford, V Gilbertson, 1999, Osteoblast fibronectin, mRNA, protein synthesis, and matrix are unchanged after exposure to microgravity, FASEB Journal, , S121-127 C Genty, 1993, Réponse in vitro des cellules ostéoformatrices aux stimuli mécaniques. Etude en microgravité réelle et sur des modèles animaux après surcharge et décharge mécaniques, PhD Thesis, Université Jean Monnet, Saint-Etienne, France, , 130-148 René Demets, WH Jansen, E Simeone, 2002, Biological Experiments on the BION-10 Satellite, SP-1208 ESA; ISBN-No. 92-9092-431-4 T Kubora, M Yamauchi, J Onozaki, S Sato, Y Suzuki, J Sodek, 1993, Influence of an intermittent compressive force on matrix protein expression by ROS 17/2.8 cells with selective stimulation of osteopontin, Archives of Oral Biology, Vol. 38, 23-31 C Genty, S Palle, Christian Alexandre, 1993, First osteoblast culture in space: cellular response to unloading, Journal of Bone and Mineral Research, 8, Suppl.1, S367 Alain Guignandon, C Genty, Laurence Vico, MH Lafage-Proust, S Palle, Christian Alexandre, 1997, Demonstration of feasibility of Automated Osteoblastic Line culture in space flight, Bone, Vol. 20, No. 2, 109-116 Laurence Vico, MH Lafage-Proust, Christian Alexandre, 1998, Effects of gravitational changes on the bone system in vitro and in vivo, Bone, 22, 5, 95S-100S |
| Temporal Coverage | 1992-12-29T00:00:00Z/1993-01-12T00:00:00Z |
| Mission Description | The HRE Data Archive (HREDA) collects information and data of investigations funded or co-funded by ESA’s Directorate for Human and Robotic Exploration (HRE) and performed on microgravity and ground-based facilities since 1972. |
| Creator Contact | https://hreda.esac.esa.int/hreda/#/pages/help/contact |
| Date Published | 2023-12-20T17:18:03Z |
| Last Update | 2024-11-21 |
| Publisher And Registrant | European Space Agency |
| Credit Guidelines | European Space Agency, 2023, 'OBLAST 1', 1.0, European Space Agency, https://doi.org/10.57780/esa-cmpr6bm |