| Name | OBLAST 1 - Osteoblastic cells in weightlessness: morphology and biochemical response |
| Operational Nomenclature | OBLAST 1 |
| URL | https://hreda.esac.esa.int/hreda/#/pages/investigation;investigationAcronym=OBLAST1_RETR |
| DOI | https://doi.org/10.57780/esa-cmpr6bm |
| Platform | Retrievable Facilities |
| HRE-E3P Category | Biology |
| Mission | Bion 10 (Cosmos 2229) |
| Keywords | ESA Human and Robotic Exploration data, HREDA dataset, Human and Robotic Exploration Data Archive, ESA exploration mission data, human spaceflight experiment data, robotic exploration telemetry dataset, International Space Station experiment data, ISS Columbus module data, microgravity research dataset, life sciences space experiment data, space physiology measurements dataset, radiation exposure measurements spaceflight, life support systems performance data, closed-loop environmental control data, ECLSS telemetry dataset, astronaut biomedical monitoring data, space habitat systems engineering data, robotic surface operations dataset, planetary exploration robotics data, lunar exploration technology demonstration data, Mars analog experiment dataset, in-situ resource utilization ISRU experiment data, space systems engineering telemetry, mission operations engineering data, payload performance dataset, calibrated experiment data products, time-series telemetry data, spaceflight sensor measurements, ESA exploration science archive data, long-duration spaceflight research dataset |
| Team Coordinator Name | Christian Alexandre |
| Version | 1.0 |
| Team Members | OBLAST1_RETR |
| Publication | Millie Hughes-Fulford, V Gilbertson, 1999, Osteoblast fibronectin, mRNA, protein synthesis, and matrix are unchanged after exposure to microgravity, FASEB Journal, , S121-127 C Genty, S Palle, Christian Alexandre, 1993, First osteoblast culture in space: cellular response to unloading, Journal of Bone and Mineral Research, 8, Suppl.1, S367 Alain Guignandon, C Genty, Laurence Vico, MH Lafage-Proust, S Palle, Christian Alexandre, 1997, Demonstration of feasibility of Automated Osteoblastic Line culture in space flight, Bone, Vol. 20, No. 2, 109-116 T Kubora, M Yamauchi, J Onozaki, S Sato, Y Suzuki, J Sodek, 1993, Influence of an intermittent compressive force on matrix protein expression by ROS 17/2.8 cells with selective stimulation of osteopontin, Archives of Oral Biology, Vol. 38, 23-31 C Genty, 1993, Réponse in vitro des cellules ostéoformatrices aux stimuli mécaniques. Etude en microgravité réelle et sur des modèles animaux après surcharge et décharge mécaniques, PhD Thesis, Université Jean Monnet, Saint-Etienne, France, , 130-148 René Demets, WH Jansen, E Simeone, 2002, Biological Experiments on the BION-10 Satellite, SP-1208 ESA; ISBN-No. 92-9092-431-4 Laurence Vico, MH Lafage-Proust, Christian Alexandre, 1998, Effects of gravitational changes on the bone system in vitro and in vivo, Bone, 22, 5, 95S-100S |
| Temporal Coverage | 1992-12-29T00:00:00Z/1993-01-12T00:00:00Z |
| Mission Description | The HRE Data Archive (HREDA) collects information and data of investigations funded or co-funded by ESA’s Directorate for Human and Robotic Exploration (HRE) and performed on microgravity and ground-based facilities since 1972. |
| Creator Contact | https://hreda.esac.esa.int/hreda/#/pages/help/contact |
| Date Published | 2025-11-08T11:34:56Z |
| Last Update | 2026-03-04 |
| Publisher And Registrant | European Space Agency |
| Credit Guidelines | European Space Agency, Christian Alexandre, 2025, 'OBLAST 1', 1.0, European Space Agency, https://doi.org/10.57780/esa-cmpr6bm |